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August 6, 1910


Author Affiliations


JAMA. 1910;55(6):468-472. doi:10.1001/jama.1910.04330060020006

Malignant diphtheria is an exceedingly serious condition with which to contend and complications of a grave nature are comparatively infrequent. The introduction of antitoxin as a routine method of treatment has reduced very markedly the malignancy of this disease making the gravest cases more benign. In fact the custom of resort to antitoxin on the very first decidedly suggestive symptom of diphtheria is so universal that statistics show the frequency of this dreaded disease to be greatly minimized. The proper management of a case of diphtheria is supposed to be a knowledge possessed by every competent physician and yet there are complications not mentioned in text-books which sometimes arise which try the skill of the most experienced clinician. A case of this kind some time ago came under my observation.

Case 1. History.—  On Sunday night, Oct. 8, 1905, I was called by telephone to a near-by town, with instructions

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