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In many malarial regions it is important that the varieties of mosquitoes common to such regions should be recognized, their breeding-habits studied and a determination made of the species of anophelines capable of transmitting the disease. This is explained by Samuel T. Darling, chief of the laboratory of the board of health of the Canal Zone, in a pamphlet issued by the Isthmian Canal Commission. The anophelines insusceptible to malaria may be more limited in their choice of breeding-places than the other varieties, so that in the work of malarial mosquito destruction the latter may be disregarded, and attention given wholly to the breeding places of those varieties responsible for the transmission of malarial fever. With regard to man as a host it is necessary to have some knowledge of the limits of his infectiousness, i. e., the number of the sexual forms of the parasite in the blood necessary
Studies in Relation to Malaria.. JAMA. 1910;55(12):1049. doi:10.1001/jama.1910.04330120071033