For some time the idea has been growing that the activity of the adrenals is materially influenced by thyroid conditions. Various clinical writers have endeavored to explain obscure symptom-complexes on this assumption, but until recently there has been no clear-cut evidence supporting the idea. Within the last two years, however, the theory has received some support from the work of several German investigators. At present, the weight of the existing evidence, although it is not entirely concordant, is in favor of the theory that the thyroids stimulate the adrenals.
During the last year and a half I have made several series of studies in the physiologic laboratories of the Harvard Medical School in an attempt to throw some further light on the relationships among the thyroids and other endosecretory organs. Although these studies are as yet for the most part incomplete, sufficient progress has been made to justify a preliminary
HOSKINS RG. THYROID SECRETION AS A FACTOR IN ADRENAL ACTIVITY. JAMA. 1910;55(20):1724–1725. doi:10.1001/jama.1910.04330200034010