To the Editor Arterial closure devices have demonstrated benefits with regard to a decrease in complications and recovery time in the setting of therapeutic arterial procedures.1 A meta-analysis left a question regarding increased complication risk vs the rapid, reliable, inexpensive, and safe alternative of manual compression.2 The Instrumental Sealing of Arterial Puncture Site–CLOSURE Device vs Manual Compression (ISAR-CLOSURE) randomized clinical trial3 was an adequately powered study that provides assurance that the studied arterial closure devices were noninferior to manual compression with regard to efficacy and complications.
Hoffer EK. Assessing the Benefit of Vascular Closure Devices After Femoral Artery Puncture. JAMA. 2015;313(8):855. doi:10.1001/jama.2015.421