December 3, 1910


Author Affiliations

Fellow of the Royal Institute for Experimental Therapeutics FRANKFORT A. M., GERMANY

JAMA. 1910;55(23):1974-1978. doi:10.1001/jama.1910.04330230032009

It is my privilege in this paper to take up the subject of specific chemical therapeutics, which is equivalent to saying that I am to expound the work that Professor Paul Ehrlich has accomplished in the past seven years, during which time he has done far more than merely lay the foundation of this new science. It can be said that this basic idea, which he has followed logically from the very beginning of his experimental work, down through his present world-stirring discovery; namely, that a specific chemical affinity exists between specific living cells and specific chemical substances, is his main, most valuable, broadest and most suggestive contribution to science.

It was this idea that was at the foundation of his famous studies on the morphology of the cellular constitution of the blood. As is known, Ehrlich was the first to describe correctly the leukocytes, and to teach us to

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