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December 31, 1910


JAMA. 1910;55(27):2302-2303. doi:10.1001/jama.1910.04330270024016

[The large amount of space occupied by the index this week makes it necessary to omit some departments and to curtail others.]

THE CAUSE OF GENERAL PARESIS  Softening of the brain, general paralysis of the insane, or, in its more modern terminology, general paresis, has become a wide-spread affection. In the therapeutic attack on it we stand helpless, and therefore any clues that may be offered regarding the factors that assist in its development are eagerly grasped at in the hope that they may lead to its conquest.Since Fournier's time the most widely accepted belief has been the syphilitic origin of paresis. Many English psychiatrists have maintained, and some even now hold, that sexual excesses, especially sexual aberrations, fellatio in particular, may cause the disorder in the absence of syphilis, but the more careful analysis of histories, the newly acquired knowledge concerning pseudoparetic syndromes in brain tumor, in arteriosclerosis,

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