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To the Editor:
—I am pleased with the editorial in the Feb. 1, 1913, issue on "Phylacogens." While I was an intern at the Boston City Hospital, I assisted Parke, Davis and Company's agent to administer the "filtrates" to a number of patients. In the majority of cases, I saw no marked improvement. The type of case that improved with "filtrates" had improved with the same rapidity under ordinary hospital treatment. In some cases relapses occurred under filtrates with such a marked increase in symptoms that the patients refused to receive any more injections. The company's representative appeared unduly enthusiastic over his results. His aim seemed to be that of gathering brilliant clinical results at any cost. There was no check put on his results in the form of control cases.P. S.—I assume that "Phylacogens" is the proprietary name for the "filtrates" of gonococcus, streptococcus, etc.
Cronin HJ. Phylacogens. JAMA. 1913;60(8):615. doi:10.1001/jama.1913.04340080055020