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August 16, 1913


Author Affiliations


JAMA. 1913;61(7):472-473. doi:10.1001/jama.1913.04350070026009

In August, 1912, I published a paper1 relating the facts in connection with my observation of fifteen cases from which an organism was isolated which I identified as a saccharomycete. This organism, which was pathogenic for white mice, all varieties of rabbits, guinea-pigs and rhesus monkeys, had been found in the sputum of patients with anomalous lung conditions, and also in a tonsil-membrane, a vaginal discharge and in a skin abscess. In most of these cases it was found mixed with other organisms, but in a few it was the only apparent cause of infection, and in these cases a disappearance of the organism was followed by alleviation and disappearance of symptoms. That report left much to be desired in the way of clinical observation of cases, necropsy reports and blood examinations. Since that time, other cases have come under my observation which have been more carefully studied, two of

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