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October 4, 1913


JAMA. 1913;61(14):1259-1264. doi:10.1001/jama.1913.04350150015006

While the question of hypertension has been thoroughly discussed during recent years, it is still one of the problems in medicine. With the introduction and general use of the sphygmomanometer, we have become acquainted with the frequency of increased blood-pressure, and have been able to follow its course; but the question of its etiology or pathologic physiology is largely undetermined. The present report is concerned merely with the present views of its etiology, a consideration of a series of cases observed during the past few years, and a brief discussion of the prognosis and treatment.

Arterial and renal changes have always been considered the most important factors in high blood-pressure. With our increasing knowledge of this subject, the importance of the renal factor has become more and more apparent, and coincidentally with this, lessened weight is attached to general arterial changes, especially if we exclude the arterial changes in the

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