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To the Editor:
—In July, 1913, a patient consulted me for attacks of a distressing coryza with sneezing, lacrimation and a reddening of the eyes. He stated that these attacks came on during June and July and appeared to be brought about while driving in the evening whenever he encountered a swarm of those ephemerids commonly called "May-flies," "Canada soldiers," "fish-flies," etc. These insects, as is well known, are abundant in the region of the Great Lakes, the imago passing its brief existence in the air, at which time the female is fertilized. The attacks from which the patient suffered had begun a few years previously and without assignable cause. The symptoms were quite like those of hay-fever without asthma, and after each one, in the absence of a repetition of the usual exciting cause, a day or two was necessary for recovery.In order to test the hypothesis of
Wilson H. Preliminary Report of a Case of Sensitization to the May-Fly (Ephemera). JAMA. 1913;61(18):1648. doi:10.1001/jama.1913.04350190066029