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January 5, 1918


Author Affiliations


From the McManes Laboratory of Experimental Pathology of the University of Pennsylvania.

JAMA. 1918;70(1):14-15. doi:10.1001/jama.1918.02600010012005

Recent studies on the epidemiology of lobar pneumonia by Dochez and Avery,1 Stillman,2 and Sydenstricker and Sutton3 have shown, in a considerable proportion of cases, that this disease arises by infection from without, because of the entrance into the upper air passages of virulent pneumococci of the fixed serologic types, contracted from persons suffering with lobar pneumonia or convalescent from this infection. In studies of a large number of healthy persons in contact with cases of lobar pneumonia due to Type I or Type II pneumococci, Avery, Chickering, Cole and Dochez4 report that about 12 per cent. were found to carry the corresponding types of pneumococci, whereas among healthy persons not in contact with cases of lobar pneumonia, these types were found in but 0.3 per cent. or less. In almost every instance these observers found that the type of pneumococcus in the carrier corresponded with that

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