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This study was undertaken to compare the frequency of positive cultures from the nasopharynx in meningococcus carriers with their frequency from other parts of the upper respiratory tract, and to determine the relation, if any, that such other parts may have to the persistence of the cocci in the nasopharynx. No reference could be found in the literature to any observations on these points.
During an extensive experience with the detection of meningococcus carriers in a large body of men under control, ninety-three segregated men, without discrimination in selection, were examined soon after isolation with regard to the presence of meningococci elsewhere than in the nasopharynx.
Cultures were made of the nasopharynx, the tonsils, the anterior superior nares, and the sputum of each individual on the same day. The examinations extended over several weeks as the carriers were detected. A sterile wire swab, with the tip bent at an angle
HERROLD RD. THE DISTRIBUTION OF MENINGOCOCCI IN THE UPPER RESPIRATORY TRACT OF CARRIERS. JAMA. 1918;70(2):82–83. doi:10.1001/jama.1918.02600020016009