It is extremely rare to find in the literature any mention of the age at which syphilis is acquired. This is probably due to the fact that by far the greater majority of chancres, particularly in the genital lesions, are contracted in early adult life through venery. Rarely is a chancre noted on the glans penis before the fifteenth or after the fortieth year. In an analysis of ninety-eight cases of chancre in private practice, the youngest was in the fifteenth year and the oldest in the fifty-eighth year, with an average age of 24 years.
There have been thousands of cases of acquired syphilis with extragenital chancre observed in the infant, and numerous cases of this type are reported in the literature. The youngest patient on record is one reported by Grünfeld,1 an infant aged 3 weeks, with a chancre on the scalp. Weil2 reports the case
HAINES WH. ACQUIRED GENITAL SYPHILIS IN THE INFANTREPORT OF CASE. JAMA. 1918;70(6):370-371. doi:10.1001/jama.1918.02600060016007