New research indicates that oxytocin, a neuropeptide associated with the development of social bonds, can markedly improve social behavior in a validated knockout mouse model of a monogenic form of autism spectrum disorder (Peñagarikano O et al. Sci Transl Med. 2015;7:271ra8).
A team led by investigators at the University of California, Los Angeles, found that juvenile knockout mice administered a single acute dose of oxytocin showed improvements in social behavior that lasted for 2 hours after treatment.
Hampton T. Oxytocin Restores Sociability in a Mouse Model of Autism. JAMA. 2015;313(9):885. doi:10.1001/jama.2015.1189