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To the Editor:
—The current comment in your issue of October 19 prompts me to call attention to the efforts of this laboratory and base hospital to do something specific for influenza. It was obvious from the first that the virus was an overwhelming one, and it was noteworthy that uncomplicated influenza was associated with leukopenia and that the complicating pneumonia raised the leukocytes very little, seemingly inadequately.In casting about for a simple, efficient and safe means to raise the leukocytes, antiserum from recovered patients was used with some profit but without a great leukocyte reaction. We then prepared a serobacterin, using the serum of patients recovered from simple influenza and from influenza complicated by pneumonia. The bacteria used were two strains of influenza bacilli, one strain each of pneumococcus Type I and Type IV, one strain of hemolytic streptococci and one strain of nonhemolytic streptococci, all recovered from
Fox H. "VACCINES IN INFLUENZA". JAMA. 1918;71(20):1682. doi:10.1001/jama.1918.02600460062022