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Article
December 7, 1918

EFFECTS OF THE INJECTION OF EPINEPHRIN IN SOLDIERS WITH "IRRITABLE HEART"PRELIMINARY NOTE

Author Affiliations

(Cambridge, Mass.) Major, M. C., U. S. Army; (Providence, R. I.); (Pendleton, Ore.); (Boston) First Lieutenants, M. C., U. S. Army; LAKEWOOD, N. J.

JAMA. 1918;71(23):1912-1913. doi:10.1001/jama.1918.26020490014010c
Abstract

On account of the general interest that has been aroused in the clinical syndrome originally described by Da Costa as the "irritable heart of soldiers," it has seemed to be advisable to present in the form of a preliminary note the observations recorded herein. No broad conclusions are as yet drawn from them. The investigations are being continued, and they will be published in detail later, when the work on the various sections is completed.

PHYSIOLOGIC ACTION OF EPINEPHRIN  In spite of the large amount of clinical and experimental work that has been done on the physiologic action of epinephrin, and on the effect of its injection into the human and animal body, our knowledge of the subject is still very far from complete. There are, indeed, not a few points on which rather fundamental differences of opinion exist among competent investigators. Nevertheless, one fact appears to be quite definitely

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