[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.158.119.60. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
JAMA Clinical Evidence Synopsis
March 24/31, 2015

Systemic Corticosteroid Therapy for Acute Sinusitis

Author Affiliations
  • 1Division Surgical Specialties, Department of Otorhinolaryngology, University Medical Center Utrecht, the Netherlands
  • 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands
  • 3Department of Family Medicine, University of Washington, Seattle
  • 4Departments of Operating Rooms and Health Evidence, Radboud University Nijmegen Medical Centre, the Netherlands
JAMA. 2015;313(12):1258-1259. doi:10.1001/jama.2014.14418
Abstract

Clinical Question  Are oral or parenteral corticosteroids associated with improved clinical outcomes in patients with acute sinusitis compared with placebo or nonsteroidal anti-inflammatory drugs (NSAIDs)?

Bottom Line  Oral corticosteroids combined with antibiotics may be associated with modest benefit for short-term relief of symptoms in adults with severe symptoms of acute sinusitis compared with antibiotics alone. Oral corticosteroids as monotherapy are not associated with improved clinical outcomes in adults with clinically diagnosed acute sinusitis.

×