Hematology today is recognized as one of our most valuable aids in the diagnosis and prognosis of acute inflammatory processes. Still, we find many who are at a loss as to the significance and interpretation of blood pictures in any given condition. In many hospitals a total leukocyte count alone is made, even though it is a well recognized fact among hematologists that of the two parts of a blood picture, that is, total leukocyte count and differential count, the latter is by far the more valuable, while the most valuable data are obtained from the comparative relation of the total leukocyte count and the polymorphonuclear percentage.
In the early days of blood counting when this branch of hematology was receiving a great deal of attention from investigators, Sondern1 published a paper which stands out as a high light among the numerous ones appearing on the subject at that
WALKER OJ. AN INDEX OF BODY RESISTANCE IN ACUTE INFLAMMATORY PROCESSESAS INDICATED BY EXAMINATION OF THE BLOOD. JAMA. 1919;72(20):1453-1457. doi:10.1001/jama.1919.02610200025011