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Comment & Response
April 7, 2015

Hypofractionated Whole Breast Irradiation for Early-Stage Breast Cancer—Reply

Author Affiliations
  • 1Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia
  • 2Anthem, Indianapolis, Indiana
  • 3Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia
JAMA. 2015;313(13):1371. doi:10.1001/jama.2015.1644

In Reply Drs Braunstein and Taghian note that patient preference may play an important role in explaining the low uptake of hypofractionated WBI among women with early-stage breast cancer in 2013. In their practice, the authors state that they discuss with patients the clinical equivalence of hypofractionated and conventional WBI. In 2013, they observed that 41% of patients opted for conventional WBI and 59% chose hypofractionation. The authors seem surprised that the rate of hypofractionated WBI was not higher; however, we take a different view of their findings.

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