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January 31, 1920


Author Affiliations

Ann Arbor, Mich.

JAMA. 1920;74(5):341. doi:10.1001/jama.1920.02620050049026

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To the Editor:  —In The Journal, January 10, p. 107, the following editorial statements appear under the above title:"We may accept these observations... without admitting their wider significance in the etiology of human nephritis.... It must be remembered that the diets used by Newburgh were potentially acid in character, and certain to produce an acid urine in a species adjusted and accustomed to secrete an alkaline fluid under a free choice of food. Until such experiments are successfully duplicated under conditions in which the normal reaction of the renal secretion is not tremendously altered and the accessory factors in the diet are known to be adequate, the incrimination of the high protein diets in connection with nephritis must be considered with judicial reserve."The writer of the editorial refuses to admit that the experiments in question bear on the problem of the cause of human nephritis because the renal

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