Nausea with occasional vomiting early in pregnancy is undoubtedly a manifestation of mild toxemia, but the condition is so familiar to every one that it attracts little attention. Patients often demand medical care because they are seriously annoyed by their "morning sickness," without arousing much concern on the part of the physician. On the other hand, many patients, because they think that this condition is to be expected during pregnancy, fail to seek advice until vomiting has progressed to the point at which it may be classed as "pernicious" or "intractable."
Despite the fact that fairly severe toxemia is not at all uncommon, and that mild toxemia is met constantly, there are many problems presented in this connection that are still without adequate explanation. There are, for instance, the questions of when to interfere and when not to interfere; which is to be a mild case of vomiting that may
TITUS P, HOFFMANN GL, GIVENS MH. THE RÔLE OF CARBOHYDRATES IN THE TREATMENT OF TOXEMIAS OF EARLY PREGNANCY. JAMA. 1920;74(12):777-783. doi:10.1001/jama.1920.02620120003002