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Clinical Trials Update
April 28, 2015

New HPV Vaccine Provides Wider Protection

JAMA. 2015;313(16):1609. doi:10.1001/jama.2015.3851

An investigational 9-valent vaccine against human papillomavirus (9vHPV) had an efficacy of nearly 97% against cervical, vulvar, and vaginal disease associated with HPV types 31, 33, 45, 52, and 58 and a similar efficacy against disease associated with HPV types 6, 11, 16, and 18 as a quadrivalent HPV (qHPV) vaccine, in a randomized trial including 14 215 women aged 16 to 26 years. Compared with current HPV vaccines, which protect against 70% of cervical cancers, 9vHPV has the potential to prevent 90% of cervical cancers (Joura EA et al. N Engl J Med. 2015;372[8]:711-723).

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