From the JAMA Network
May 5, 2015

Ramelteon for Prevention of Delirium in Hospitalized Older Patients

Author Affiliations
  • 1School of Medicine, Department of Geriatrics, University of Antwerp, Antwerpen, Belgium

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2015;313(17):1745-1746. doi:10.1001/jama.2014.17394

Delirium is a transient global disorder of cognition and is very common in hospitalized patients. Nearly 30% of older patients (age >65 years) experience delirium at some time during hospitalization, and 40% of older patients admitted to intensive care units will have delirium.1 Risk factors for delirium include dementia, stroke, Parkinson disease, and sensory impairment. Polypharmacy (particularly the use of psychoactive drugs), infection, dehydration, the use of restraints, and catheters have been associated with the development of delirium.

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