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JAMA Clinical Guidelines Synopsis
May 12, 2015

Screening for Hepatitis C

Author Affiliations
  • 1Section of Hospital Medicine, University of Chicago Medical Center, Chicago, Illinois
JAMA. 2015;313(18):1855-1856. doi:10.1001/jama.2015.2833

Hepatitis C virus affects an estimated 180 million people worldwide, making it the most common chronic blood-borne pathogen.1 Less than half of infected individuals clear their infection without treatment, and 15% to 40% of patients with HCV progress to cirrhosis or hepatocellular cancer. Hepatitis C virus infection is the most common indication for liver transplantation and is the cause of 8000 to 13 000 deaths in the United States each year.2

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