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To the Editor The study by Dr Noto and colleagues,1 a single-center, multiple crossover, cluster randomized clinical trial involving 9340 patients admitted to 5 ICUs at a tertiary care medical center compared daily bathing with chlorhexidine against washing with nonantimicrobial cloths. Chlorhexidine bathing did not reduce the incidence of health care–associated infections.
Soto-Hernandez JL. Chlorhexidine Bathing and Infections in Critically Ill Patients. JAMA. 2015;313(18):1863. doi:10.1001/jama.2015.3533