JAMA Clinical Evidence Synopsis
May 19, 2015

Antidepressant Treatment for Postnatal Depression

Author Affiliations
  • 1Health Service and Population Research Department, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, United Kingdom

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JAMA. 2015;313(19):1965-1966. doi:10.1001/jama.2015.2276

Clinical Question  Are antidepressants associated with improved outcomes for postnatal depression?

Bottom Line  Compared with placebo, selective serotonin reuptake inhibitors (SSRIs) are associated with better response and remission rates for postnatal depression. However, few studies included women with severe depression or suicidal ideation. There are insufficient data to conclude whether antidepressants are associated with better outcomes than psychological interventions.