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From the JAMA Network
May 26, 2015

Variation in Prostate Cancer Care

Author Affiliations
  • 1Dow Division of Health Services Research and Department of Urology, University of Michigan, Ann Arbor
JAMA. 2015;313(20):2066-2067. doi:10.1001/jama.2015.0607

The use of many medical and surgical therapies varies widely between clinicians and geographic regions. Perhaps nowhere is this more evident than in the treatment of men with early-stage prostate cancer. For this group of patients, there is substantial variation not only in the use of any local therapy (vs observation), but also in the use of specific treatment modalities. The former concern is particularly salient among men with low-risk prostate cancer, a group for whom the survival benefits of local therapy are less clear, while the potential adverse effects, including urinary and sexual dysfunction, may be no less apparent. Because surgery and radiation may represent overtreatment for some men with low-grade tumors, several clinical guidelines now recommend initial observation (usually in the form of active surveillance) for patients with low-risk disease.1

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