Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
The new US precision medicine initiative1 has been made possible by improvement and price reduction in genome sequencing, as well as advances in multiple sectors of biotechnology. The initiative includes 2 components: a focus on cancer intended to spur development of new targeted cancer treatments, and a proposal for establishing a national cohort of at least 1 million people to explore genetic and environmental determinants of health and disease. The success of this initiative requires a public health perspective to help ensure generalizability, assess methods of implementation, focus on prevention, and provide an appropriate balance between generation of long-term knowledge and short-term health gains.
Khoury MJ, Evans JP. A Public Health Perspective on a National Precision Medicine CohortBalancing Long-term Knowledge Generation With Early Health Benefit. JAMA. 2015;313(21):2117-2118. doi:10.1001/jama.2015.3382