It is difficult, if not impossible, to present the subject of endocrine dysfunction in a brief article, without appearing to be both ignorant and dogmatic; ignorant of many alleged facts, because time does not permit giving the reasons for their rejection, and dogmatic because practically every statement made in regard to the ductless glands today requires qualification, which is, for the most part, ruled out by the time limit. Furthermore, I take part in this discussion with the diffidence of a man whose personal experience is limited largely to the experimental side of the subject. However, I have a fair acquaintance with the entire endocrine literature, in both the field of science and the field of fiction, and I take for granted that we all subscribe to the principle that the rules of evidence or criteria for facts are the same in the experimental and in the clinical fields.
CARLSON AJ. HYPOFUNCTION AND HYPERFUNCTION OF THE DUCTLESS GLANDS. JAMA. 1922;79(2):98-104. doi:10.1001/jama.1922.02640020010004