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September 16, 1922

The Etiology and Pathology of Typhus. The Main Report of the Typhus Research Commission of the League of Red Cross Societies to Poland.

JAMA. 1922;79(12):990. doi:10.1001/jama.1922.02640120064035

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This is an important contribution to the study of typhus fever. Lice, reared from uninfected stock and free from rickettsia-like organisms and disease virus of all kinds, when allowed to feed on typhus patients became infective and acquired Rickettsia prowazeki, which the authors regard as the cause of typhus. The experiments yielding these results appear flawless. To mention just one detail: To insure that the lice used would be free from all such organisms, nits were obtained from a dispensary in Montreal and hatched out on members of the expedition. The causal rôle of the rickettsia bodies is indicated further by their presence in the lesions of human and guinea-pig typhus, but the attempts to cultivate these bodies all failed. The illustrations are excellent. The book is printed on heavy calendered paper; the size is large octavo, 7½ by 10½ in., but the printed page covers only 4½ by 7

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