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November 4, 1922


Author Affiliations

From the Department of Internal Medicine, University of Michigan Medical School.

JAMA. 1922;79(19):1591-1593. doi:10.1001/jama.1922.02640190029010

In consideration of the frequency of pleural effusion in general, it is surprising that so few cases of pleural effusion with a large number of eosinophils have been reported in the literature. It is surprising also that the tubercle bacillus as the etiologic agent in these cases has never been isolated from the exudate. Bayne— Jones1 states that this condition occurs in about 1 to 5 per cent, of all pleural effusions, as determined by investigators applying constant methods to cases in series. Schwartz2 compiled sixty-eight cases from the literature in his monograph on the subject of eosinophilia. Klein3 has reported two cases. One was a right-sided pleural effusion following an operation for hemorrhoids, the necropsy revealing septic, thrombosed hemorrhoidal veins, which were believed by the prosector to have been the source of the pleural infection. A second case followed stab wounds in the chest, which resulted

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