To those who have had experience with tropical malaria, the protein nature of this disease is only too well known. Its syndrome, its wide range and its variation of symptoms and signs, together with its complex symptomatology are as complicated as those of syphilis, and it is as dangerously imitative of symptoms and syndromes of other maladies, for which reasons it is not always one of the easiest diseases to eliminate in a difficult differential diagnosis in tropical medicine.
Many self-explanatory names have been assigned to the various forms of pernicious type of subtertian or estivo-autumnal malaria, such as hyperpyrexial, the delirious and comatose, the aphasic, convulsive, tetanic, epileptiform, apoplectic, general paralytic, meningeal, and the cerebellar and bulbar types. In 1917, I1 reported a case presenting all the signs of anterior poliomyelitis. Various psychoses and memory disturbances, as well as impairment of good judgment and reasoning, have been directly
BROSIUS OT. CEREBRAL MALARIAREPORT OF AN UNUSUAL CASE. JAMA. 1924;83(11):841–842. doi:10.1001/jama.1924.02660110039012