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From the JAMA Network
June 16, 2015

A Revised Quality Measure for Surgical CareMore Alpha Testing for Perioperative β-Blockers?

Author Affiliations
  • 1Department of Surgery, University of Toronto, Toronto, Ontario, Canada
  • 2Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada
  • 3Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
  • 4Division of Support, Systems, and Outcomes, Toronto General Research Institute, Toronto, Ontario, Canada
  • 5Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  • 6Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
JAMA. 2015;313(23):2369-2370. doi:10.1001/jama.2015.0798

Myocardial infarction is an important cause of disability and death after surgery, prompting interest in interventions to reduce the incidence of perioperative cardiovascular events. Since the 1980s, perioperative β-adrenergic blockers have been examined as a strategy to reduce the risk of perioperative myocardial ischemia in patients undergoing noncardiac surgery. β-Blockers may prevent the rupture of coronary plaques due to the physiologic stress of surgery1 and can reduce myocardial oxygen demand associated with catecholamine excess in the postoperative period.2

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