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January 25, 1930

SERUM DISEASE AND SERUM ACCIDENTS

Author Affiliations

COOPERSTOWN, N. Y.; NEW YORK
From the Medical Service of the Mary Imogene Bassett Hospital, Cooperstown, N. Y., and the Department of Medicine, Columbia University College of Physicians and Surgeons, New York.

JAMA. 1930;94(4):260-265. doi:10.1001/jama.1930.27120300002010
Abstract

This report was prepared at the request of the Council on Pharmacy and Chemistry. The Council considered the report, approved it, and authorized its publication.

W. A. Puckner, Secretary.

A little more than forty years ago, Hericourt and Richet established the principle of passive immunization. They demonstrated that the blood of an animal immunized by repeated injections of a micro-organism contains something which protects an otherwise untreated animal against infection by the organism used to immunize the first animal. The discovery of this important principle of passive immunization prepared the way for the production of diphtheria antitoxin in 1890 by von Behring and for all the other therapeutic serums and antitoxins which have been offered to the medical men of the present generations. The prophylactic or therapeutic value of a few of these serums is beyond question; of some, the most that can be said is that they are probably

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