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October 25, 1924


Author Affiliations

Gary, Ind.

JAMA. 1924;83(17):1355. doi:10.1001/jama.1924.02660170071032

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To the Editor:  —The article of Dr. Laurence E. Hines on "Accidental Malarial Infection in Syphilis of the Brain" (The Journal, October 11) leaves a wrong impression on the mind of the reader, since it criticizes a method of treatment not according to the facts. Professor Wagner-Jauregg, who inaugurated the malaria treatment of general paralysis (The Journal, Aug. 4, 1923, p. 405; Medizinische Wochenschrift, No. 13, 1924) expressly emphasizes the point that the blood of patients suffering from estivo-autumnal fever should never be used, but only that of tertian malaria. The fever induced by inoculation of tertian malarial blood is promptly controlled by quinin, the plasmodia disappearing after the administration of 1 gm. of the drug. Arsphenamin is given simultaneously with the quinin treatment. The reports from abroad are very favorable with this method of treatment; Wagner-Jauregg and Pilcz report 100 per cent, of cures and remissions in the early

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