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February 15, 1930


JAMA. 1930;94(7):496-497. doi:10.1001/jama.1930.02710330050021

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Experimental Encephalitis and Dementia Paralytica  Mr. Levaditi, of the Institut Pasteur, has made an observation that appears to explain the pathogenesis of dementia paralytica. In experimental encephalitis produced in animals with the spirochete of recurrent fever, he found that these parasites, which are usually found only in the granular form, appear sometimes in the form of spirilla when they have disappeared from the other organs. He concludes from this that the infection of the brain with the spirochete which occurs in dementia paralytica is of the same nature. The organism recovers its spirillar form coincident with the attacks of apoplectiform icterus, while in the intervals it persists in the latent state in the brain in the granular form.

Discussion on Embolism  The Société de chirurgie de Lyon recently discussed the subject of fatal embolism. Mr. Patel had observed six cases: four after fractures of the neck of the femur, two

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