March 10, 1923


JAMA. 1923;80(10):709-710. doi:10.1001/jama.1923.02640370045022

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Measles as Modified by Preventive Injections of Convalescents' Serum  The method of prophylaxis of measles by the injection of the serum of convalescents from this disease, which has been recommended, since 1916, by C. Nicolle and E. Conseil, and which has been widely experimented with in America and in Germany, has been the subject of a series of studies in France (P. L. Marie, Nobécourt and Paraf, Cheinisse). However, at a recent meeting of the Société médicale des hôpitaux de Paris, Drs. R. Debré and Ravina held up against the method the transitory character of the immunity it confers. By a previous injection of convalescents' serum, they have proposed to secure an attenuated type of measles in children who become exposed rather than to suppress the disease entirely. To accomplish such a result, a preventive injection at the end of the period of incubation, between the seventh and the tenth

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