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December 13, 1924

GLANDULAR THERAPYPHYSIOLOGY OF THE MAMMALIAN OVARIES

JAMA. 1924;83(24):1920-1923. doi:10.1001/jama.1924.26610240002012
Abstract

Because of the limited space for this review, I am excluding consideration of ovarian physiology below mammals. In the mammalian group there is a fair degree of uniformity in female sex life, the outstanding variations being the absence of the phenomena of menstruation in mammals below the primates, the varying frequency of estrus, and such anatomic characters as horns being sex distinctive in some species and not in others.

THE FEMALE SEX LIFE OF MAMMALS  The complexity of the physiologic processes in the mammalian female that depend, directly or indirectly, on ovarian functions is indicated by the following outline:

  • Preadolescent Period.

    1. Fetal sex differentiation. There is now considerable evidence that in the mammals such differentiation of sex characters as takes place in the female fetus during intra-uterine life depends on hormones from the anlage of the future ovaries.

    2. Preadolescent nutrition of uterus and mammary glands and such differentiation of the

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