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March 1, 1930

Sonderbände zur Strahlentherapie.

JAMA. 1930;94(9):659. doi:10.1001/jama.1930.02710350059043

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This is a codification of facts dealing with immediate and remote injury from radiotherapy. The author emphasizes the fact that every act of irradiation comprises an intervention into the physiochemical function of the bodily cells analogous to the action of powerful drugs. One must distinguish between the local and the general action of therapeutic rays. In the last instance the whole problem of irradiation, including the avoidance of untoward harm, is a dosimetric proposition. The injuries inflicted are divided into reversible and irreversible ones. In the special part the harmful consequences of irradiation are discussed as appearing in the skin and in the deeper situated organs, and the deleterious influence on the general somatic condition. Dermatitis, ulcerations and roentgen cancer are thoroughly discussed. Instructive histologic expositions of the harm produced are given. The administration of the proper prophylactic measures and their evaluation are presented. Particular attention is paid to the

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