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JAMA Clinical Guidelines Synopsis
June 23/30, 2015

Perioperative β-Blocker Therapy

Author Affiliations
  • 1University of Chicago, Chicago, Illinois
JAMA. 2015;313(24):2486-2487. doi:10.1001/jama.2015.3086

Routine use of β-blockers to prevent cardiac complications related to noncardiac surgery began in the 1990s after the publication of 2 influential randomized clinical trials (RCTs).1,2 Responding to this evidence, a 2002 ACC/AHA guideline published a strong recommendation for starting β-blockers in high-risk patients undergoing vascular surgery and stated that this was also reasonable in moderate- to high-risk patients undergoing major noncardiac surgery.

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