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Article
January 24, 1925

DENTAL INFECTIONS AND RELATED DEGENERATIVE DISEASESSOME STRUCTURAL AND BIOCHEMICAL FACTORS

JAMA. 1925;84(4):254-261. doi:10.1001/jama.1925.02660300012006
Abstract

The relationships between dental infections and degenerative diseases, if such exist, should be demonstrable by other means than the establishment of simply an association of the two in the same person, or the development of such lesions in experimental animals with cultures taken from focal infections. In this paper I summarize some new data developed in my researches on the relation of focal infection to systemic disease, with particular consideration of dental focal infections and the degenerative diseases, and with especial reference to structural changes that take place in the supporting structures about dental focal infections, and to serologic changes in body serums.

In a previous communication 1 I have given a preliminary report, indicating that patients can be divided into three groups on the basis of the type of structural change that develops in the supporting structures of infected teeth, as the result of the presence of a given

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