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July 7, 1923


JAMA. 1923;81(1):44-45. doi:10.1001/jama.1923.02650010048015

It is only natural that a cause for diseases that seem unintelligible should be sought in the disturbance of functions about which we know little. Probably the most baffling common disease, if it is a disease and not, as many believe, a catch-all for psychiatric flotsam and jetsam, is that described under the name of dementia praecox. As the name is now used, the cases included in this group comprise approximately 50 per cent, of all admissions to hospitals for mental diseases and an even larger proportion of the total population of such institutions at any given time. The most fascinating and at the same time the least understood of all realms in physiology is that of the endocrine glands. Much effort has been directed to establishing a valid connection between these two sets of phenomena, which range from the now discredited Abderhalden reactions and studies of metabolism to the

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