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April 12, 1930


JAMA. 1930;94(15):1148-1149. doi:10.1001/jama.1930.02710410040015

Interest in the physiologic activity of calcium has a long history, but only within comparatively recent years have some of the finer details of its biochemical behavior been determined. Since the greater part of the calcium of the body is in the bones, studies of their normal and abnormal development have yielded valuable information concerning this element. As a result, the inclusion of some source of vitamin D in the diet, the exposure to sunlight or to artificial ultraviolet rays, and strict attention to the quantity and proportion of phosphorus and calcium in the food are today accepted nutritional requirements for normal skeletal growth in young animals. Furthermore, there is a considerable mass of both experimental and clinical evidence that shows a close relationship between the parathyroid glands and calcium metabolism. It is striking that the level of calcium in the blood can be raised not only by the various

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