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We have here a fairly brief up-to-date exposition of our knowledge of cholethiasis, a discussion of the most prominent theories on this subject, and a review of its medical therapy. The interesting fact is quoted that, although necropsy statistics in general show an incidence of gallstones of about 12 per cent. for Germany, in Russia and Japan these are found in only 2 or 3 per cent. of all bodies. A deeper study of these observations might lead to a better knowledge regarding the prophylaxis. The author favors the idea of Kehr and Strauss that the hunger pain of cholelithiasis is due to tension of an excessively filled gallbladder due to insufficient frequency of meals. As Frerichs and Naunyn have shown, food is the best cholagogue; and frequent meals are of advantage to patients with gallstones. In duodenal intubation, the author injects into the duodenum, according to the suggestion of
Die Gallensteinkrankheit, Richtlinien der inneren Klinik.. JAMA. 1923;81(7):602. doi:10.1001/jama.1923.02650070086032