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May 16, 1925


Author Affiliations

Washington, D. C.

JAMA. 1925;84(20):1515. doi:10.1001/jama.1925.02660460051032

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To the Editor:  —I have read the letter of Dr. M. K. Amdur of Cleveland (The Journal, May 2, p. 1375) commenting on my article in The Journal, April 11, on the malaria treatment of paresis. Since my article was written, a second group of forty-seven patients with paresis, has been treated, and the inoculations were made practically as described by Dr. Amdur, except that none were made intravenously. In addition, those who failed of inoculation in the first group reported and those who were still living were reinoculated. In spite of this there were thirteen patients who failed to develop malaria. Of the second group mentioned, two were inoculated with infected mosquitoes. Of these two, one had malaria and the other did not.I differ with Dr. Amdur's statement about the nontransmissibility of artificial malaria. It is not uncommon for asexual forms of the parasite in the human blood

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