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The pathogenicity of Giardia has always been a debatable question. Without citing any arguments, we record a case that would seem to prove that here at least it can be considered the causative agent of disease. Incidentally, as far as we have been able to determine, it is the first case recorded of Giardia in the kidney pelvis:
REPORT OF CASE
E. M. C., a white woman, aged 27, single, schoolteacher, a native of California, who came under observation, July 9, 1929, had suffered from amebiasis in 1923, diagnosed from a stool examination by Dr. Kofoid of the University of California Medical School. She was under treatment periodically for the next two years, therapy consisting of subcutaneous injection of some drug the name of which she never learned. At no time was there blood in the stool. In addition, she was told that the stool contained Trichomonas and Giardia; oral
Ayer EW, Neil JM. PROTOZOA IN THE URINARY TRACT. JAMA. 1930;94(19):1489-1490. doi:10.1001/jama.1930.27120450001009