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June 14, 1930


JAMA. 1930;94(24):1931-1932. doi:10.1001/jama.1930.02710500049025

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Early Syphilitic Hemiplegia  Drs. Gilberto Moura Costa and Waldemiro Pires of the Gaffrée-Guinle Foundation recently published an article on early syphilitic hemiplegia. Hemiplegia occurs frequently in syphilis. Fournier believes that hemiplegia as a rule appears between the sixth, and the tenth years from the onset of syphilis. Among 213 patients with vascular syphilis of the nervous system seen by the authors, hemiplegia developed between the fifth and the twelfth years after the primary chancre. Hemiplegia may be either an early or a late manifestation of syphilis. In a case reported by Jakob, hemiplegia developed fifty years after the chancre, and in some cases it appears after the first year. In the clinic of neurosyphilis of the Gaffrée-Guinle Foundation, the authors observed fourteen cases of early hemiplegia, in nine of which hemiplegia appeared one year after the development of the chancre, in three cases five months after, and in two cases

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