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Article
October 10, 1925

PERIRENAL SCLEROSIS (CHRONIC CICATRIZING PERINEPHRITIS)REPORTS OF TWO CASES OCCURRING AS A SEQUEL TO PERINEPHRITIC ABSCESS

JAMA. 1925;85(15):1118-1120. doi:10.1001/jama.1925.02670150016005
Abstract

Perinephritic abscess has been the subject of extensive review in medical literature. On the other hand, the more chronic inflammatory conditions which result in sclerotic thickening of the renal capsule have received but slight consideration.

Inflammation of the fibrous and fatty investment of the kidneys, perinephritis in the narrower sense of the term, may accompany all the acute and chronic processes that disturb the kidney; and depending on the variety of the inflammation, leads to thickening, adhesions with the renal parenchyma or subcapsular suppuration.

Whether extensive perirenal suppuration occurs or not, a persistent indurative process may continue until the perinephritic fat and fibrous capsule of the kidney become converted into an unyielding cicatricial shell.

Hartmann,1 one of the earliest writers on this subject, considers that nonsuppurative perinephritis is an important pathologic entity because of the adhesions which it causes between the kidney and surrounding organs. He describes this as

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