A moderate degree of splenomegaly is a frequent finding during the course of syphilitic infection. Marked splenomegaly is sometimes encountered, and Giffin2 has reported three such cases which were treated surgically because of absence of improvement under antisyphilitic treatment. Other cases3 have been reported in which splenomegaly was associated with syphilis accompanied by a clinical picture resembling Banti's disease We have been unable to find in the literature the report of a case similar to the one reported here, in which the clinical picture at first suggested an atypical leukemia, and later Banti's disease, and in which antisyphilitic treatment was attended by marked improvement.
REPORT OF CASE
—A widowed white man, aged 47, seen Aug. 25, 1924, complained of pains in the left side of the abdomen and chest, and weakness. His father had died at the age of 59 from alcoholism, and his mother had died
Elkin A, Bowcock HM. A CASE OF MARKED SPLENOMEGALY AND LYMPHOCYTOSIS ASSOCIATED WITH SYPHILIS. JAMA. 1925;85(15):1135-1136. doi:10.1001/jama.1925.26710150002011b