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July 12, 1930

Memoranda on the International Standardization of Therapeutic Sera and Bacterial Products.

JAMA. 1930;95(2):149. doi:10.1001/jama.1930.02720020065037

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Perhaps no phase of activity of the League of Nations Health Section more closely affects physicians than the standardization of therapeutic serums and bacterial products. The difficulties encountered during the World War, when the allied countries employed different units for diphtheria and tetanus antitoxin, are still fresh in one's mind. Thanks to the Health Section, international standard preparations of antidiphtheritic, antitetanic and antidysenteric serums are now available. This summary by Professor Prausnitz gives the technical aspects of the standardization of the antiserums mentioned as well as antimeningococcus, antipneumococcus and antistreptococcus serums, which are considered therapeutic rather than antitoxic. The author also discusses blood group determinations and points out the confusion caused by the employment of either the Moss or Jansky nomenclatures and the recommendation of the 1928 Standardization Conference to return to the old von Dungern and Hirschfeld nomenclature (AB, A, B and O). A section is devoted to the

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